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SA, from the Anderson article you quoted:
– …Subsequent generation of a polybasic cleavage site would have then required repeated passage in cell culture or animals with ACE2 receptors similar to those of humans, but such work has also not previously been described. Finally, the generation of the predicted O-linked glycans is also unlikely to have occurred due to cell-culture passage, as such features suggest the involvement of an immune system.
But that’s precisely the work described in the suspect grant applications – studying enhanced coronaviruses by culturing them in transgenic mice, genetically modified to have human ACE2 receptors. Mice do of course have an immune system. You wrote:
– “So the authors do not dismiss this possibility, but actually give their reason, based on actual knowledge and experience, of why this could not be the case.”
I disagree. The authors seem to have evaded the point by going on about cell cultures rather than the actual allegation which very clearly specifies experiments in humanised mice. There is also this from the Anderson piece:
– “Furthermore, a hypothetical generation of SARS-CoV-2 by cell culture or animal passage would have required prior isolation of a progenitor virus with very high genetic similarity, which has not been described.”
Yes, but that’s the whole point of getting the WIV-Ecohealth genetic database opened – you know, the one that was quietly taken off-line by Ecohealth shortly after the seriousness of the outbreak was realised, and now everyone’s accusing the Chinese government of hiding.
Neither companies nor governments should be entitled to “confidentiality”. Secrecy kills. If what they’re doing is for public benefit as they claim, it should be all out in the open. If it’s merely for private profit, all the more reason for transparency.